Approach to bilateral parotidomegaly

'SLAM' the face

(S)
- Sjogren's disease (Look for dry eyes / month)
- Sarcoidosis (hilar lymphadenopathy, lupus pernio, hepatomegaly)

(L)
- Lymphoma / Leukaemia (anaemia, oral ulcers, bruising, hepatomegaly, splenomegaly, lymphadenopathy)

(A)
- Amyloidosis
- Alcoholic excess (evidence of chronic liver disease, neuropsychiatric manifestations, CAGE questionnaire)

(M)
- Mumps (also examine male genitalia)& many infections (e.g. HIV, EBV, CMV, coxsackie A, influenza, TB)
- Metabolic (starvation / bulimia, hyperlipidaemia) & endocrine (e.g. DM, chronic pancreatitis, acromegaly, hypothyroidism)