Wednesday, May 7, 2008

Reading: Procalcitonin

Today I was asked to order procalcitonin test for a patient with suspected infection.
The patient was well, no particular localising symptoms currently. However approximately 2 weeks ago he was treated as probable meningoencephalitis with improvment of headache & diplopia. Lab results returned normal, and an informative lab message showed:

" Procalcitonin: +ve if elevated suggestive of bacterial / parasite / fungal infections. It may not be raised in localised infection, chronic inflammation, or chronic autoimmune diseases. It is not usually elevated in fracture / surgery, and rarely exceeds 5. Procalcitonin begins to rise after onset of infection in 2hrs, peaks in 12 - 24 hours, and 1/2 life 22 - 29 hours".

Attacked reference: wikipedia (inside contain reading links)

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